
Muhammad Sarfraz Nawaz MD
Dr. Muhammad Sarfraz Nawaz is a board‑certified hematologist and medical oncologist at Hematology Oncology of Indiana and Assistant Clinical Professor at Marian University College of Osteopathic Medicine. Trained at Creighton University (Internal Medicine) and Augusta University (Hematology/Oncology), he combines deep clinical experience with an active research portfolio spanning solid‑tumor oncology, malignant hematology, and quality‑improvement science. Fluent in five languages, Dr. Nawaz is known for delivering compassionate, evidence‑based care while mentoring the next generation of physicians.
About Dr. Muhammad Sarfraz Nawaz MD
Dr. Muhammad Sarfraz Nawaz is a board‑certified hematologist and medical oncologist at Hematology Oncology of Indiana and Assistant Clinical Professor at Marian University College of Osteopathic Medicine. Trained at Creighton University (Internal Medicine) and Augusta University (Hematology/Oncology), he combines deep clinical experience with an active research portfolio spanning solid‑tumor oncology, malignant hematology, and quality‑improvement science. Fluent in five languages, Dr. Nawaz is known for delivering compassionate, evidence‑based care while mentoring the next generation of physicians.
- 15+ years clinical experience
- 20+ peer‑reviewed publications
- 30+ conference abstracts & posters
- 5 languages spoken (English, Urdu, Hindi, Punjabi, Saraiki)

Personal Note: “Outside the clinic Dr. Nawaz enjoys swimming, piano, pickleball, soccer, and countryside trips with his family.”
Education Timeline
CLINICAL EXPERTISE
Dr. Nawaz manages the full spectrum of adult cancers and blood disorders with particular expertise in solid‑tumor oncology and malignant hematology.
Breast Cancer
Dr. Nawaz provides comprehensive care for all types of breast cancer, including early-stage, locally advanced, and metastatic disease. Treatment plans are personalized and may include chemotherapy, hormonal therapy, targeted therapy, and coordination with surgical and radiation teams. He emphasizes patient education, support through survivorship, and close monitoring of treatment response.
Thoracic (Lung) Cancers
Expert in managing non-small cell and small cell lung cancers, as well as other thoracic malignancies like mesothelioma. Dr. Nawaz uses the latest advances in targeted therapies and immunotherapy. He works closely with pulmonologists and thoracic surgeons to ensure an integrated, multidisciplinary approach.
Genitourinary (Kidney, Prostate, Bladder)
Dr. Nawaz treats cancers of the kidney, prostate, bladder, and testicles, offering both standard and advanced systemic therapies. He is experienced in managing hormone-sensitive and castration-resistant prostate cancer and collaborates with urologists for surgical and surveillance strategies.
Gastrointestinal & Pancreatic Cancers
Care includes treatment of colorectal, pancreatic, liver, bile duct, stomach, and esophageal cancers. Dr. Nawaz focuses on precision medicine approaches and combines chemotherapy with emerging therapies to maximize outcomes. Coordination with gastroenterologists and surgeons ensures comprehensive care.
Lymphoma & Chronic Lymphocytic Leukemia
Experienced in treating both Hodgkin and non-Hodgkin lymphoma, as well as CLL. Dr. Nawaz incorporates novel agents, immunotherapies, and clinical trial options when appropriate. He also provides long-term monitoring for disease remission and recurrence.
Multiple Myeloma
Provides advanced care for patients with newly diagnosed or relapsed/refractory multiple myeloma. Dr. Nawaz utilizes modern regimens including proteasome inhibitors, immunomodulatory drugs, monoclonal antibodies, and stem cell transplant coordination.
Benign & Malignant Hematology (anemia, thrombosis, coagulation)
Manages a broad range of blood disorders, from iron-deficiency anemia and clotting abnormalities to complex hematologic malignancies. Dr. Nawaz offers diagnostic expertise and individualized treatment plans, including anticoagulation management and supportive transfusion care.
Supportive‑Care Services:
- Symptom control & survivorship
- Chemotherapy education & infusion management
- Coordination with radiation oncology & surgery
📚 RESEARCH & PUBLICATIONS
Lead‑in:
Committed to advancing cancer care, Dr. Nawaz maintains an active clinical‑research program exploring novel therapeutics and health‑services outcomes.
Featured Publications
- “Patterns of CAR‑T Adoption in Multiple Myeloma: A Midwest Consortium Analysis” – ASCO 2024 poster.
- “Real‑World Febrile Neutropenia Outcomes After Order‑Set Standardization” – Journal of Oncology Practice (2023).
- “Evolving Role of Bispecific Antibodies in Relapsed/Refractory Follicular Lymphoma” – Blood Advances (2022).
🏅AWARDS & HONORS
- Castle Connolly Top Doctor 2024
- WebMD Preferred Provider 2023‑24
- ACP Indiana – 1st Place Oral Vignette 2024
- US News & World Report – Patients’ Top Choice 2024



TEACHING & SPEAKING
As an Assistant Clinical Professor, Dr. Nawaz delivers bedside teaching sessions, oncology noon conferences, and CME lectures nationwide.
- Moderator – ASH 2024 Satellite Symposium on Myeloma Sequencing
- Grand Rounds – “Managing Febrile Neutropenia in 2025” – Ascension St Vincent
- PRIME Education – CME Faculty, 10 accredited programs (2022‑2024)
QUALITY‑IMPROVEMENT & LEADERSHIP

Dr. Nawaz leads quality initiatives that translate research into better patient outcomes.
- Standardized Febrile‑Neutropenia Order‑Set (HOI, 2024 – present) – 25% reduction in time‑to‑antibiotics
- ‘Inject Plerixafor at 5 p.m.’ Fellowship QI – improved stem‑cell harvest efficacy
🌍INDUSTRY ENGAGEMENT & DISCLOSURES
Transparency is central to ethical oncology practice.
Dr. Muhammad Sarfraz Nawaz serves on advisory boards for AstraZeneca, Daiichi‑Sankyo, Gilead, Janssen, AbbVie, and Genentech. He also participates in speakers’ bureaus for Bristol Myers Squibb and Pharmacosmos.
Disclosure date: May 2024
Relevance: These engagements are unrelated to the content of the ACP Indiana 2024 Oral Clinical Vignette presentation.
Conflict of Interest Statement: Dr. Nawaz affirms that all potential conflicts of interest have been disclosed in accordance with ACP guidelines.
LOCATIONS & CONTACT
Main Office: Hematology Oncology of Indiana
8301 Harcourt Rd, Suite 200
Indianapolis, IN 46260
Fax: (317) 415‑6605
Satellite Clinics:
- Witham Cancer Center – Lebanon
- Ascension St Vincent Fishers – Fishers
- Ascension St Vincent Breast Center – Carmel
(Full addresses available on request)